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Effects of LED Light Therapy - Highlights of Journal Articles
"But if the rats were treated with LED light with a wavelength of 670 nm for 105 seconds at 5, 25 and 50 hours after being dosed with methanol, they recovered 95 per cent of their sight. Remarkably, the retinas of these rats looked indistinguishable from those of normal rats. 'There was some tissue regeneration, and neurons, axons and dendrites may also be reconnecting,' says Whelan."
"We believe that the use of NASA Light-Emitting Diodes (LED) for light therapy will greatly enhance the natural wound healing process, and more quickly return the soldiers to a pre-injury/ illness level of activity. The use of LED in combat with self-healing patches in future may enable the soldiers even after they are wounded to persist in combat better and longer."
http://www.asc2002.com/Abstracts_only/d/DA-06.pdf
"LED produced improvement of greater than 40% in musculoskeletal training injuries in Navy SEAL team members, and decreased wound healing time in crew members aboard a U.S. Naval submarine. LED produced a 47% reduction in pain of children suffering from oral mucositis. CONCLUSION: We believe that the use of NASA LED for light therapy alone, and in conjunction with hyperbaric oxygen, will greatly enhance the natural wound healing process, and more quickly return the patient to a preinjury/illness level of activity. " "ATS treatments improve sensation in the feet of subjects with DPN, improve balance, and reduce pain."
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11776448
"This technology may be the answer for problem wounds that are slow to heal....diabetic skin ulcers and other wounds in mice healed much faster when exposed to the special LEDs in the lab. Laboratory research has shown that the LEDs also grow human muscle and skin cells up to five times faster than normal...."
"Light close to and in the near-infrared range has documented benefits for promoting wound healing in human and animals. "
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11568632
"ATS treatments improve sensation in the feet of subjects with diabetic peripheral neuropathy, improve balance, and reduce pain."
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&list_uids=14693984
"Near-infrared irradiation potentially enhances the wound healing process, presumably by its biostimulatory effects."
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&list_uids=11722751
" It was found that laser exposure resulted in more pronounced restoration of functional state of nervous fibers than conventional therapy. Application of laser irradiation of low intensiveness was effective while in combined therapy of distal diabetic polyneuropathy as well as monotherapy."
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&list_uids=9677693
"exposure of volunteers to visible and infrared polarized (VIP) light leads to a fast increase in the growth promoting (GP) activity of the entire circulating blood for human KCs in vitro, which is a consequence of the transcutaneous photomodification of blood and its effect on the rest of the circulating blood volume."
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&list_uids=14743286
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&list_uids=14521091
"The method of monochromatic near infrared stimulation can be used for selective stimulation of several regions of the external auditory canal,.."
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&list_uids=14999583
LED and LLL irradiation resulted in an increased fibroblast proliferation in vitro. This study therefore postulates possible stimulatory effects on wound healing in vivo at the applied dosimetric parameters.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&list_uids=12928819
Wound healing was significantly more rapid with than without FIR. Skin blood flow and skin temperature did not change significantly before or during far-infrared irradiation.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&list_uids=12773705
Although more studies are needed, LED therapy appears useful in the prevention of OM in pediatric BMT patients.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi
News articles on the NASA Study:
http://garm.dyndns.org/whelan_lab/01/html/%20/whelan.html
http://www1.msfc.nasa.gov/NEWSROOM/news/releases/2000/00-336.html
http://healthlink.mcw.edu/article/975450257.html
http://www.hypography.com/article.cfm?id=29173
http://www.viahealth.org/via_news/news2002/april/woundstudy.htm
http://www.engr.wisc.edu/industry/atwork/vol5/WCSAR.html
http://www.scienceblog.com/community/older/archives/D/archnas202.html
A wound-healing device was placed on the USS Salt Lake City submarine, and doctors reported 50 percent faster healing of crewmember's lacerations when exposed to the LED light. Injuries treated with the LEDs healed in seven days, while untreated injuries took 14 days.
second daily infrared (JR) laser (820 nm, 25mW) and visible red laser (670 nm, 10 mW) at 1 J/cm2 and 5 J/cm2 on chronic pain. ...five treatment sessions over a two-week period. ...significant reductions in pain over the duration of the study with those groups which received infrared (820nm) laser a 1 J/cm2 and 5 J/cm2
904 nm three times weekly for 2 weeks, ......tendonitis of the shoulder
3.5-inch by 4.5-inch (89-millimeter by 114-millimeter), portable flat array of LEDs, arranged in rows on the top of a small box. ......places the box of LEDs on the outside of the patient's cheek about one minute each day. The red light penetrates to the inside of the mouth, where it seems to promote wound healing and prevent further sores in the patient's mouth.
All 176 patients received six treatments during a period of 3-4 weeks. ..GAAs laser therapy for tendinitis and myofascial pain
A 40 year-old woman presented at the Abe Orthopedic Clinic with a 2-year history of lower back pain and pain in the left hip and leg diagnosed as a ruptured disc between the 5th lumbar/1st sacral vertebrae. .....The gallium aluminum arsenide (GaAlAs) diode laser (830 nm, 60 mW) was used in outpatient therapy, and after 7 months, the patient's condition had dramatically improved, demonstrated by motility exercises. This improvement was confirmed by further MRI scans, which showed clearly the normal condition of the previously herniated L5/SI disc.
Influence of low-level (810nm, GaAlAs semiconductor) laser on bone and cartilage during joint immobilization was examined with rats' knee model. .......The hind limbs of 42 young Wistar rats were operated on in order to immobilize the knee joint. One week after operation they were assigned to three groups: irradiance 3.9W/cm2, 5.8W/cm2, and sham treatment. After 6 times of treatment for another 2 weeks both hind legs were
myofascial pain in the cervical region. The patients were submitted to 12 sessions on alternate days to a total energy dose of 5 J each.
RA:From July 1988 to June 1990, 170 patients with a total of 411 affected joints were treated using a GaAlAs diode laser system (830 nm, 60 Mw C/W). Patients mean age was 61 years
890 nanometer (nm)....Venous ulcers, diabetic ulcers, and post-amputation wounds....It recently has been demonstrated that application of this particular MIRE device to the skin for 30 minutes increases plasma NO in nondiabetic subject volunteers, as measured with a Sievers Instrument, Model 280, Nitric Oxide Detector
"But if the rats were treated with LED light with a wavelength of 670 nm for 105 seconds at 5, 25 and 50 hours after being dosed with methanol, they recovered 95 per cent of their sight. Remarkably, the retinas of these rats looked indistinguishable from those of normal rats. 'There was some tissue regeneration, and neurons, axons and dendrites may also be reconnecting,' says Whelan."
"We believe that the use of NASA Light-Emitting Diodes (LED) for light therapy will greatly enhance the natural wound healing process, and more quickly return the soldiers to a pre-injury/ illness level of activity. The use of LED in combat with self-healing patches in future may enable the soldiers even after they are wounded to persist in combat better and longer."
http://www.asc2002.com/Abstracts_only/d/DA-06.pdf
"LED produced improvement of greater than 40% in musculoskeletal training injuries in Navy SEAL team members, and decreased wound healing time in crew members aboard a U.S. Naval submarine. LED produced a 47% reduction in pain of children suffering from oral mucositis. CONCLUSION: We believe that the use of NASA LED for light therapy alone, and in conjunction with hyperbaric oxygen, will greatly enhance the natural wound healing process, and more quickly return the patient to a preinjury/illness level of activity. " "ATS treatments improve sensation in the feet of subjects with DPN, improve balance, and reduce pain."
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11776448
"This technology may be the answer for problem wounds that are slow to heal....diabetic skin ulcers and other wounds in mice healed much faster when exposed to the special LEDs in the lab. Laboratory research has shown that the LEDs also grow human muscle and skin cells up to five times faster than normal...."
"Light close to and in the near-infrared range has documented benefits for promoting wound healing in human and animals. "
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11568632
"ATS treatments improve sensation in the feet of subjects with diabetic peripheral neuropathy, improve balance, and reduce pain."
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&list_uids=14693984
"Near-infrared irradiation potentially enhances the wound healing process, presumably by its biostimulatory effects."
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&list_uids=11722751
" It was found that laser exposure resulted in more pronounced restoration of functional state of nervous fibers than conventional therapy. Application of laser irradiation of low intensiveness was effective while in combined therapy of distal diabetic polyneuropathy as well as monotherapy."
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&list_uids=9677693
"exposure of volunteers to visible and infrared polarized (VIP) light leads to a fast increase in the growth promoting (GP) activity of the entire circulating blood for human KCs in vitro, which is a consequence of the transcutaneous photomodification of blood and its effect on the rest of the circulating blood volume."
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&list_uids=14743286
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&list_uids=14521091
"The method of monochromatic near infrared stimulation can be used for selective stimulation of several regions of the external auditory canal,.."
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&list_uids=14999583
LED and LLL irradiation resulted in an increased fibroblast proliferation in vitro. This study therefore postulates possible stimulatory effects on wound healing in vivo at the applied dosimetric parameters.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&list_uids=12928819
Wound healing was significantly more rapid with than without FIR. Skin blood flow and skin temperature did not change significantly before or during far-infrared irradiation.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&list_uids=12773705
Although more studies are needed, LED therapy appears useful in the prevention of OM in pediatric BMT patients.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi
News articles on the NASA Study:
http://garm.dyndns.org/whelan_lab/01/html/%20/whelan.html
http://www1.msfc.nasa.gov/NEWSROOM/news/releases/2000/00-336.html
http://healthlink.mcw.edu/article/975450257.html
http://www.hypography.com/article.cfm?id=29173
http://www.viahealth.org/via_news/news2002/april/woundstudy.htm
http://www.engr.wisc.edu/industry/atwork/vol5/WCSAR.html
http://www.scienceblog.com/community/older/archives/D/archnas202.html
A wound-healing device was placed on the USS Salt Lake City submarine, and doctors reported 50 percent faster healing of crewmember's lacerations when exposed to the LED light. Injuries treated with the LEDs healed in seven days, while untreated injuries took 14 days.
second daily infrared (JR) laser (820 nm, 25mW) and visible red laser (670 nm, 10 mW) at 1 J/cm2 and 5 J/cm2 on chronic pain. ...five treatment sessions over a two-week period. ...significant reductions in pain over the duration of the study with those groups which received infrared (820nm) laser a 1 J/cm2 and 5 J/cm2
904 nm three times weekly for 2 weeks, ......tendonitis of the shoulder
3.5-inch by 4.5-inch (89-millimeter by 114-millimeter), portable flat array of LEDs, arranged in rows on the top of a small box. ......places the box of LEDs on the outside of the patient's cheek about one minute each day. The red light penetrates to the inside of the mouth, where it seems to promote wound healing and prevent further sores in the patient's mouth.
All 176 patients received six treatments during a period of 3-4 weeks. ..GAAs laser therapy for tendinitis and myofascial pain
A 40 year-old woman presented at the Abe Orthopedic Clinic with a 2-year history of lower back pain and pain in the left hip and leg diagnosed as a ruptured disc between the 5th lumbar/1st sacral vertebrae. .....The gallium aluminum arsenide (GaAlAs) diode laser (830 nm, 60 mW) was used in outpatient therapy, and after 7 months, the patient's condition had dramatically improved, demonstrated by motility exercises. This improvement was confirmed by further MRI scans, which showed clearly the normal condition of the previously herniated L5/SI disc.
Influence of low-level (810nm, GaAlAs semiconductor) laser on bone and cartilage during joint immobilization was examined with rats' knee model. .......The hind limbs of 42 young Wistar rats were operated on in order to immobilize the knee joint. One week after operation they were assigned to three groups: irradiance 3.9W/cm2, 5.8W/cm2, and sham treatment. After 6 times of treatment for another 2 weeks both hind legs were
myofascial pain in the cervical region. The patients were submitted to 12 sessions on alternate days to a total energy dose of 5 J each.
RA:From July 1988 to June 1990, 170 patients with a total of 411 affected joints were treated using a GaAlAs diode laser system (830 nm, 60 Mw C/W). Patients mean age was 61 years
890 nanometer (nm)....Venous ulcers, diabetic ulcers, and post-amputation wounds....It recently has been demonstrated that application of this particular MIRE device to the skin for 30 minutes increases plasma NO in nondiabetic subject volunteers, as measured with a Sievers Instrument, Model 280, Nitric Oxide Detector
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